Cabergoline excretes in the urine and stool. Besides this, it gets absorbed in the body and is metabolized in the liver. A few medications decrease the cabergoline effectiveness and enhance the potential for experiencing some side effects. The physician should therefore, establish clear management of the drug and prescribe only the minimum amount required.

Some women who experience microprolactinomas have the menstruation begin to return after sometimes on treatment. Such women should forgo pregnancies and nursing their babies. They should observe these because their drugs suppress lactation.

It Reduces Proclactin Concentration

Cabergoline Bodybuilding Tablet is a dopamine agonist that has a specific and potent inhibitory effect on prolactin secretion by rat pituitary lactotrophs in vitro. It reduces serum prolactin levels in hyperprolactinemic patients and normalizes PRL levels in 86% of those with idiopathic hyperprolactinemic disorders or micro- or macroprolactinomas93. It also alleviates pretreatment symptoms in 92% of those with a idiopathic hyperprolactinemic disorder and in 77% of those with a macroadenoma94.

The major activity of Cabergoline is mediation of its ability to bind onto the D2 receptors of the brain leading to inhibition of prolactin secretion by affecting the release of a hormone named bFGF, brain-derived follicular growth factor that stimulates release of prolactin. This pharmacological activity acts almost in exactly the same ways bromocriptine (a DPP-4 inhibitor). This drug already is well documented for use to help control prolactin-secreting tumors.

Most patients will not experience major complications during long-term Cabergoline therapy. But some people experience rare side effects: valvular heart disease and even a dangerous acute fall in blood pressure referred to as orthostatic hypotension. Your endocrinologist will have close follow-up of your blood tests and MRI scans for such potential complications.

The drug should not be administered when one is breastfeeding as it will suppress the production of milk, and it will also make the baby malnourished. Always notify your endocrinologist that you want to breastfeed, and they will inform you how you should handle the situation.

It Decreases the Estrogen Levels

Cabergoline is a long-acting tablet treatment for hyperprolactinemia, the production of too much prolactin by your pituitary gland. It reduces the production of prolactin by binding to dopamine receptors and prevents your body from releasing this hormone. It also aids in the reduction of a tumor in your pituitary gland known as a prolactinoma. Dostinex is its brand name.

This drug has been shown to be effective in the treatment of menstrual irregularities in PCOS patients with moderate hyperprolactinemia. It does not delay periods or cause ovulation problems. Approximately 70 to 80 percent of women who take Cabergoline ovulate and are able to become pregnant.

This is a dopamine agonist that has recently been developed. It has a potent antitumorigenic effect and binds to dopamine receptors, blocking them from receiving prolactin signals. This results in a dramatic and sustained decrease in blood prolactin levels, the longest ever seen with an ergot derivative.

Cabergoline may be taken with or without food. One must follow their physician's prescription about dosing and avoid any other drugs that would interfere with the action of this drug. Cabergoline should not be taken with antibiotics like erythromycin and clarithromycin and anti-nausea and antiemetic drugs such as domperidone and metoclopramide, respectively, since these elevate the levels of cabergoline in your blood and thereby diminish its effect.

It Lowers Testosterone Levels

A male patient presented to Charing Cross Hospital with five months of gynecomastia and low libido due to macroprolactinoma. He had an MRI of the pituitary gland, which showed a 119 mm adenoma. He was given cabergoline and his serum prolactin became normal in six weeks. He then regained full libido and sexual potency. His testosterone levels also normalized.

This hormone prolactin is produced mainly in the pituitary gland and is essential for mammals to be able to produce milk. However, it tends to over-produce in females causing issues including irregular periods, unwanted breast milk, and infertility. Cabergoline works on the brain by combining itself with dopamine receptors preventing the same from producing the hormone prolactin. This shows its results in as few as three days and lasts a number of weeks.

Cabergoline is an oral medication that is available in tablet form. Your doctor will begin with a low dose and gradually increase it over a period of several months. Be sure to follow your doctor's instructions to the letter.

The patients are followed with pituitary MRI scans and blood tests. A few of them enter into remission, where their treatment could be withdrawn. Nonetheless, use of non-hormonal contraceptives (e.g. barrier contraception) is mandatory as well as letting the endocrinologist know of becoming pregnant on the drug.

Reduces Luteinizing Hormone Levels

Cabergoline is a drug used to control the condition of an excessive amount of production of prolactin in the human body. Besides hyperprolactinemia, cabergoline is also useful for the cure of certain problems of menstruation and infertility of women, also in the management of pituitary prolactinomas-a type of tumor for the pituitary gland. It works on the brain where it stops the further production and releasing of prolactin. These conditions can either be treated solely by this medicine or in combination with other drugs.

This drug can only be prescribed by a doctor. It comes in the form of a tablet that you orally take. Your doctor may start you on a low dose and gradually increase it. You must inform your doctor about the drugs you are currently taking; this includes prescription and non-prescription drugs, vitamins, and herbal dietary supplements. Of special importance, discuss with your physician if your age is greater than or equal to 65 years. This is because your body clears this medicine more slowly, which heightens the risk of side effects.

The most common side effect of cabergoline is dizziness or lightheadedness when you get up from a lying or sitting position. It usually gets worse when you just start taking it. To help prevent this, lie down or stand up slowly.

Other serious but rare side effects include a heart condition that leads to difficulty breathing, ankle swelling, or chest pain. It can also cause an extremely rare condition known as fibrosis, where organ tissue scars and hardens. This generally occurs in the lungs, around the heart, and behind the stomach.